are both top tier unlocks! When used, this will combine with your other active item, creating a unique flame and possibly giving special effects, The recharge time of this item is based on your 2nd active item, otherwise it's 4 rooms, While held, guarantees the first Devil/Angel Room encountered to be an Angel Room, and increases the overall chance of getting one, A maximum of 16 flames can be active at one time around Isaac, Counts as 1 of 3 book items needed towards the Bookworm transformation, UNLOCK: Unlock this item by defeating Isaac as Bethany, A single use active item that will spawn 3 soul hearts and 2 items from the Angel Room pool, Starts fully uncharged and gains charges only through picking up soul and black. Using it with less than 5 coins does nothing, UNLOCK: Unlock this item by collecting 99 coins then spending all of them in the same run, Item Pool: Item Room, Greed Mode Item Room, Upon use, grants use of Brimstone for the current room, If used twice in the same room, the brimstone laser becomes massive and deals +1.8 more damage, Using it more than twice in the same room will give a damage increase each time. rocks), Item Pool: Item Room, Devil Room, Greed Mode Devil Room, * item room, treasure room, item room pool, luigi board, weeja board, paper, grown, Automatically gives you 1 bar of charge after using your spacebar item, Fully recharges your current spacebar item when picked up, Any items which are normally a 1 room recharge are now timed instead, * shop room pool, shop item pool, battery, black, brown, When Isaac takes damage, the dead bird will spawn and attack nearby enemies in the current room for 2 damage per tick, * item room, treasure room, item room pool, the lost item pool, starting, grey, gray, Tears are replaced with the ability to charge and fire a powerful laser that travels in a straight line across the room, dealing a lot of damage (tear damage hits for 9 ticks per laser) to any enemies it comes into contact with, Does not directly affect your Damage stat but hits enemies 9 times per charge, Synergizes very well with a lot of items including Tammy's Head, Tiny Planet, Inner Eye (Triple Shot), Mutant Spider (Quad Shot) and many others, If you somehow manage to get a second Brimstone, the laser becomes massive and deals double damage, * devil pool, devil room pool, devil deal, infinity, red, black, Has a chance to drop while playing any Blood Donation machine, UNLOCK: Unlock this item by playing the Blood Donation machine 30 times, Item Pool: None (Blood Donation machine only), Gives you a high rate of fire in exchange for a damage down, * secret room pool, item room, treasure room, item room pool, Thin Odd Mushroom, brown, purple, grey, gray, REPENTANCE - Odd Mushroom (thick) is now a larger damage increase (equal to that of Steven/Pentagram), but now also a larger speed downgrade (from -0.1 to -0.2), * secret room pool, item room, treasure room, item room pool, purple, pink, brown, thick odd mushroom thick, When you only have half a red heart remaining or less, you enter a curse state which adds +1.5 damage and +0.3 speed, When playing as Eve, this item activates with one FULL heart remaining or less AND also removes her 0.75 damage multiplier, raising it up to 1.0, The effect is permanently active for characters with no red hearts (e.g. ?, Satan and The Lamb as Tainted Samson, When taking damage you have a chance to explode and deal 185 damage to all enemies around you (Same damage as a Mr. Mega bomb), UNLOCK: Unlock this trinket by defeating Mother as Tainted Samson, Familiars follow Isaac's exact movements, (similar to how Jacob & Esau work) instead of following loosely like they usually do, Holding the drop button (Ctrl on Steam version) causes them to stop moving, Doesn't affect some familiars with specific movement patterns, e.g. They can be used to damage enemies, Saturnus tears can't break objects such as poop and TNT barrels, Isaac now shoots ice tears that slow enemies. grey, gray, blue, moms eyeshadow, Tears now have a chance to concuss enemies, causing them to walk around dazed and confused for a short period of time, The chance to concuss enemies is affected by your luck stat and at +27 Luck it will activate every time, * item room, treasure room, item room pool, grey, gray, silver, ingot. Now grants a half black heart upon use instead of a full soul heart. 2 keys = 16.6% chance. It will also sometimes randomly drop bombs. The mod-turned-official-DLC has upended Isaac's . you could find a caves boss in the basement. Tears continue to fire from your left eye, The laser deals damage equal to 1/7th of your tear damage, but very rapidly, The laser can apply status effects (e.g. More items consumed = more chance for this effect. After a minute or so of not hurting her she will fly away and spawn Plum Flute, UNLOCK: Unlock this item by allowing Baby Plum to escape instead of killing her, Spawns a star with a white aura around it, that floats very slowly through each room on the floor, making its way towards the boss room, While standing inside the aura, you gain a big Tears Up (x2.5 fire rate), Damage Up (damage * 1.2 + 1) and homing tears, The star continues to make its way through the floor, even if you aren't in the same room as it, moving faster if you are a long distance ahead of it, On The Void floor, it will move towards the boss room containing Delirium, Doesn't travel into the Hush or Mega Satan boss room, It may travel through secret/curse rooms on its route to the boss room, Counts as 1 of 3 astrology items needed in the same run to unlock Planetariums, UNLOCK: Unlock this item by defeating Delirium as Bethany, Gives you a baby in an ice cube, which can be kicked around the room by walking into it, Enemies take damage from Cube Baby depending on how fast it was travelling when it hit them. This allows Isaac to potentially accrue a large number of stat upgrades. If there are no enemies this pill spawns 1-3 blue spiders instead, One makes you smaller - Reduces Isaac's size and hitbox size, One makes you larger - Increases Isaac's size, but does not affect the size of his hitbox, Percs - Causes Isaac to only take half a heart of damage from all sources for the current room (The Wafer effect). are now magnetically attracted to Isaac's tears, Can cause some enemies to have unpredictable movement, * item room, treasure room, item room pool, grey, gray, magnet, Tears are now charged up and fired rapidly in a burst of up to 5 shots at once, The amount of tears fired in the charge depends on how long you charge for, The eye has three states, white (not firing), black (first second of charging) and blinking between black and white. 1 = poop, 2 = penny, 3 = bomb, 4 = key, 5 = red heart, 6 = pill, 7 = card, 8 = soul heart, 9 = gold heart, 10 = gold key, 11 = gold bomb, At the full 12 charges, a completely random effect will happen. "The Binding of Isaac: Rebirth". Spikes and Curse Rooms no longer deal damage, Sharp Plug becomes useless with this item, due to how damage is prevented on Isaac's body, REPENTANCE - Isaac's Heart has a charge attack, which pushes enemies away and fires blood tears in all directions. REPENTANCE - Bob's Brain now has an increased delay before becoming available when entering rooms. as Bethany, Gives you a random syringe effect every room, The effect can be The Virus, Roid Rage, Speed Ball, Experimental Treatment, Synthoil, Euthanasia or Growth Hormones, Placed bombs explode after 0.66 seconds instead of the usual 1.5 seconds, This was called Exploded Firecracker in Antibirth, Farts produced by Isaac or familiars will be twice as large, Chance for enemies to burn when entering a room, The chance for this effect to activate is effected by your Luck stat, This includes key blocks and golden chests, Pickups left on current floor will appear in the starting room of the next floor, up to a maximum of 4 pickups, Active items will be rerolled upon using them, Using with Book of Virtues will only reroll the item the book is holding, Has no effect with Notched Axe due to how its durability works, UNLOCK: Unlock this trinket by defeating Mother as Eden, Random luck-based tear effects have an extra chance of occurring, The additional chance is effectively +3 Luck Up, Picking up red hearts now has a high chance to spawn 1-4 blue attack spiders, instead of giving you health back, This effect also works while fully healed, giving a guaranteed chance of getting spiders, While missing any red health the chance for spiders is less, Works for characters that don't use red health, which always gives you spiders, Hearts in Shops can be converted into spiders for free, Gives your familiars improved rate of fire while held, In Antibirth this trinket was called Song of the Siren, UNLOCK: Unlock this trinket by bombing the skull left by The Siren boss after her death, While held at the start of each floor, this trinket spawns four wisp familiar orbitals around Isaac, These wisps are the same as the ones created by the Book of Virtues item, UNLOCK: Unlock this trinket by beating the Boss Rush as Bethany, Your active item no longer gains charges, but battery drops become much more common, UNLOCK: Unlock this trinket by blowing up 10 Battery Beggars, Tears that miss enemies will redirect themselves and travel 90 degrees towards enemies, Tears must be roughly 2 tiles or closer to activate this effect, +10 Luck while held, but the trinket is destroyed when damage is taken, Blood donation machines, Curse Rooms and Sacrifice Rooms wont destroy it, Taking a hit and activating Holy Mantle won't destroy it, Can be dropped in order to avoid breaking it, This trinket is automatically given to you after clearing 3 bosses without taking damage, Treasure Rooms are replaced with Red Treasure Rooms, which contain a deal with the devil in place of a regular item pedestal, If an item room has not yet been entered, it can be transformed to either a regular or Red Treasure Room by picking up or dropping this trinket before entering, Does not affect the mirrored treasure room in Downpour II, UNLOCK: Unlock this trinket by defeating Mother as Azazel, Every time you pick up a coin, you have a small chance to gain 1 bar of charge on your active item, The chance for this effect to happen is 1/6th of the value of the coin picked up, Can only activate once per coin collected, In Antibirth this trinket was called Electric Penny, UNLOCK: Unlock this trinket by donating to a battery beggar until he pays out with an item 5 times, While held, your familiars will now orbit around Isaac instead of following behind him, Activates your active item just before damage would be taken, It doesn't activate for free - the charges are used up as normal if this effect activates. See the Broken Shovel / Mom's Shovel items for more information on how to unlock, Rotten Hearts fill up a whole container the same as normal red hearts, or the rightmost heart if you're at full health, Every time you clear a room, you'll spawn 2 Blue Flies for each Rotten Heart you currently have, UNLOCK: Unlock this by entering the Corpse floor for the first time, Spawns 2-3 pills, black/bone hearts and/or bombs when picked up, Can spawn in place of a regular sack, including in Shops for 7c, Only one heart can spawn per sack as a maximum, UNLOCK: Unlock this by defeating Mega Satan as Tainted Judas, 48 Hour Energy - Fully recharges your active item and drops 1-2 battery pickups. The charge time is based on your tears stat. Stat options are: +1.0 Damage, +0.6 Tears, +0.2 Speed, +5.25 Range, Also drops either a bomb, a key or 3 coins on the ground. Fire Dips burn enemies and leave a fire behind on death. After entering a Planetarium the chance goes back to 1%. Defeating Mega Satan as one of the B-side characters unlocks a whole new object a la Lucky Pennies. pants, under wear, pink, knickers, moms underwear, mom underwear, REPENTANCE - Touching enemies deals 12 damage to them, Item Pool: Boss Room, Challenge Room, Mom's Chest, * dungeon room, blood challenge room, arena pool, boss room pool, boss room item, red, high, shoe, moms heels, mom heels, Drops a random heart on the floor when picked up, * moms lipstick, mom lipstick, dungeon room, blood challenge room, arena pool, boss room pool, boss room item, red, grey, gray, UNLOCK: Unlock this item by beating Mom's Heart 4 times, Gives Isaac angel wings for the current room, allowing him to fly, Instantly kills the Mom's Foot, Mom's Heart and It Lives boss fights, If used during the Satan fight, The Bible will instantly kill Isaac, Counts as 1 of 3 angel items needed towards the Seraphim transformation, REPENTANCE - Reduced to 4 room recharge time, * library pool, library room, book room pool, angel room pool, god room pool, angel room item, While you have this flame you also have that item's effect, The flame deals double your tear damage to any enemies that touch it, but if it takes too much damage the flame will disappear and you lose the item's effect, Wisps are randomly chosen from Item Room, Boss Room and Shop item pools, with a 25% chance to pick the same pool as the current room. The longer the button is held the faster Gurdy will fling itself across the screen, Deals a fixed amount of damage depending on charge level, at lowest being ~5 and at max being ~20, Lil Gurdy bounces off of enemies and obstacles, A beggar head which floats around the room and picks up any nearby coins. You may see more or less than this on the Found HUD overlay, however this number varies based on your other damage increasing items. Confuses all enemies briefly when destroyed, White poop - Same effect as Hallowed Ground, Stone poop - Deals extra thrown damage, can hit multiple enemies. 2 keys = 50% chance. This brings you to the maximum possible speed, The effect lasts for the rest of the current floor, UNLOCK: Unlock this item by defeating Mother as Samson, Isaac gains a halo of light around him. I want to add that almost EVERY tainted character have something interesting added to game after beating mega satan. (6 full hearts to fully charge), Unless fully charged, hearts picked up are consumed by the Alabaster Box, instead of being added to your life total. treasure room, item room pool, yellow, golden, ring, circle, Item Pool: Item Room, Shop, Challenge Room, Beggar, Demon Beggar, Mom's Chest, * dungeon room, blood challenge room, arena pool, demon beggar pool, demon judgement pool, devil beggar pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, item room, treasure room, item room pool, yellow, red, blue, medicine, jar, drug, moms bottle of pills, Tears now have a random chance to apply a poison effect, causing double your tear damage per tick to enemies over time, The chance to fire poison shots is affected by your luck stat and at +12 Luck it will activate every time, * item room, treasure room, item room pool, green, snot, booger, ball, slime, Isaac's tears now split into two upon contact with enemies or the environment, Tears that split off from the main tear do less damage (tear damage * 0.5), Tears can keep splitting if they still have range and damage above 1, UNLOCK: Unlock this item by collecting two of the following items: Bob's Rotten Head, Dead Cat, Cricket's Head, Tammy's Head, * item room, treasure room, item room pool, pink, slug, bug, face, When used, replaces all pedestal items in the current room with another random item. * golden chest pool, gold chest pool, item room, treasure room, item room pool, green, ball, Tap the drop button to cycle between each one, All future pill drops will now instead become cards, * shop room pool, shop item pool, packet, deck, brown, orange, Allows for 2 pills to be held. Caves 2: 1 Boss Item + 2 Soul Hearts, Depths 1: 4 Soul hearts. Clots returning back to Eve deal 3x damage as they suck back in, The type of heart consumed to create a clot will give it different abilities: Soul Hearts = More health, Black Hearts = Dark Matter effect, Eternal Hearts = Sacred Heart effect, Gold Hearts = Midas Touch effect, Bone Hearts = Compound Fracture effect, Rotten Hearts = Less health, Tainted Eve starts with this item, but can be used by any character after unlocking it and finding it in the item room, UNLOCK: This item comes along with Tainted Eve. With the nerf to the Devil Room pool quality overall, this item is the strongest new addition to that pool. This item will modify drops from room clearing and champion enemies based on your current player state. Unlock Condition: Collect 3 Astrology related items (Zodiac items, fortune-teller related items, etc.). You must make it back through the path solving a few bomb puzzles while avoiding her, to get back to the regular floor. The Lost starts with this item after donating 879 coins to the Greed Donation Machine. Everything does at least one full heart of damage. Counts as 1 of 3 familiar items needed towards the Conjoined transformation. After which, the only way to access an Angel Room is via the Sacrifice Room, * curse room pool, red chest pool, red chest item pool, golden chest pool, gold chest pool, devil pool, devil room pool, devil deal, brown, horns, When depleted, Black Hearts deal 40 damage to the entire room, in a Necronomicon style effect, * curse room pool, demon beggar pool, demon judgement pool, devil beggar pool, devil pool, can t use carpenter's workbench skyrim; how long does it take a rat to starve to death; cowboy hat making supplies; why would i get a letter from circuit clerk Eden - Spawns 3 items from any pools, you can only take 1, The Lost - Useless items like HP upgrades, spectral tears or flight are removed from the item pools, Lilith - Causes all your offensive familiars to stack tightly infront of Lilith for more controlled damage, Apollyon - Void has a chance to spawn a previously destroyed item as well. Tears are now white, do a lot more damage and move slower across the screen with a homing effect, * angel room pool, god room pool, angel room item, red, fire, flame, orange, cross, Does not increase your damage, simply makes your tears red, * boss room pool, boss room item, sticks, brown, yellow, * angel room pool, god room pool, angel room item, the lost item pool, cup, wooden, gold, The mirrored floor rooms have respawned enemies, and allows you to optionally fight the Boss a second time for an extra item, When combined with Knife Piece 2, can be used to stab the fleshy door in the Mausoleum II, which then leads to the Corpse floor and the Mother boss, Combine with Knife Piece 1 to create a Knife which can be fired across the room, dealing 25 damage to any enemies it comes into contact with, In the Mines/Ashpit II, there's a room with a minecart and a broken track. Gives a small chance when entering a room for enemies to be petrified for 4 seconds. Midnight Snack = +1 flat damage, +1 luck. This is to prevent a syngery like Dr. Fetus or a Golden Bomb giving you infinite resources, Isaac's shadow will follow closely behind him and when it comes into contact with enemies, will spawn friendly dark charger mobs, The chargers deal contact damage to enemies, and will be killed if it is hurt too much, Chargers disappear upon entering a new room, UNLOCK: Unlock this item by beating Greed Mode with Judas, Every time you kill an enemy a fly will be added to the Jar, allowing you to stack up to 20, Using the Jar of Flies will release all the flies that are currently in the jar as friendly flies that will damage enemies, A Loki familiar that follows Isaac and shoots tears 4 tears in a cross pattern, dealing a flat 3.5 damage each, Gives Isaac a familiar glass of milk that follows him and spills on the floor upon taking damage, After being spilt, the milk gives you a -2 Tear Delay (Tears up) for the rest of the room, When used, the D7 will restart the current room and bring back all enemies once again, enabling you to farm rewards that spawn at the end after beating the room, Can be used to generate infinite consumable combinations, gaining as many coins/keys/bombs as you need, This item has no effect in Greed Mode, Challenge Rooms and rooms that had no enemies in originally, If used in a Boss Room or Angel/Devil Room, you get teleported to another random room, which is reset instead of the boss/angel/devil room you were in, Enemies respawned by the D7 don't drop loot if they were champions and also don't grant score in daily runs, * dice, pip, die, turban, white, grey, gray, Makes Isaac very small like a baby, reducing his hitbox size, When used, Mom's Box will drop a random trinket on the ground, While held, doubles the effect of trinkets which make sense to be doubled (e.g. The poison deals your tear damage per tick, for 2 ticks, Has no effect on Lilith, as she cannot fire tears, While firing tears constantly for 7.5 seconds, you spawn a poop cloud, which deals periodic damage to any enemies which come near it, The cloud deals damage equal to your base tear damage per tick, roughly 5 times per second, Clouds last 15 seconds before disappearing, The cloud can be pushed slightly by firing tears at it, Upon taking damage, Isaac starts to bleed, leaving a trail of blood and spraying blood tears everywhere which deal damage to nearby enemies, While bleeding, Isaac takes damage every 30 seconds, The blood sprays in the direction you are current firing, or just randomly near Isaac if not shooting your tears, The blood spray scales with your current tear damage and any future damage increases, This effect lasts until you pick up a red heart, Upon taking damage, this item gives a 25% chance to drop a full red heart, REPENTANCE - This entire item has been reworked, Enemy bullets have a 25% chance to be deflected back at the enemy, which will hurt them and apply the concussive status effect, causing it to be stunned for a few seconds, Every 20th tear fired will also fire a golden coin tear at the same time. Frozen enemies can be pushed into obstacles where they shatter on contact and fire ice shards around them. Also summons a blue crosshair which can be moved around freely. UNLOCK: Unlock this item by beating the Isaac boss with Azazel, * the satanic bible library pool, library room, book room pool, devil pool, devil room pool, devil deal, item room, treasure room, item room pool, the lost item pool, pentagram, star, grey, gray, red, When used, fires a 4 way brimstone laser in all cardinal directions, dealing a lot of damage to any enemies, Laser damage does not scale with your damage stat - its a fixed 10 damage per tick for 20 ticks (200 total per use), Has a chance to drop after you beat Krampus, If you get close enough to an enemy that has a large hitbox, you can hit it with 2 of the laser beams, allowing you to deal more damage, UNLOCK: Unlock this item by beating Krampus (Krampus is unlocked by taking 20 devil deal items), *, horns, grey, gray, white, red, dead, tongue, krampus head, When used, farts on nearby enemies and knocks them backwards away from Isaac, Allows you to reflect projectiles away from Isaac, REPENTANCE - Butter Bean now knocks back enemies and projectiles with significantly more force. lightning, bolt, hot garbage, Tears now have a bigger knockback effect, which pushes enemies backwards, * astrology, astronomy, item room, treasure room, item room pool, h, blue, glow, Tears Down by exactly half (Tear delay * 2), The tears down from this item is a x2.0 multiplier after the formula, meaning it will always halve your tear rate (Unless you have Monstro's Lung or Soy Milk), UNLOCK: Unlock this item by beating Boss Rush with Eve, * item room, treasure room, item room pool, makeup, make up, black, grey, gray, square, eves mascara, When you die with this item, you respawn in the previous room as Dark Judas with 2 black hearts for health, Dark Judas has a damage multiplier of 2.00 (double Isaac's damage) and an additional +0.1 Speed, Dark Judas is considered a separate character by the game, however he can be used to unlock Judas' secrets/achievements, REPENTANCE - Dark Judas can no longer gain red heart containers, HP upgrades give soul hearts instead, UNLOCK: Unlock this item by beating Boss Rush with Judas, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool judas shadow, All future red hearts now heal for double. Can cause white poops through other item effects such as A Card Against Humanity or Re-Lax pills. Of all the tear replacer effects, I find that this isn't the strongest one overall and it's a bit tough to use, plus it overrides literally everything else. linda hamilton macgyver; horse pasture rd pickens sc; orchard hills country club membership cost; mi compromiso contigo amor * item room, treasure room, item room pool, white, purple, Gives Isaac the ability to fly and spectral tears, * devil pool, devil room pool, devil deal, red, crescent, moon, drop, black, Creates 5 beams of light from the sky that deal damage equal to your tear damage + 20 to any enemies which come into contact with them, The beams have a high chance to spawn on top of enemies where possible, * item room, treasure room, item room pool, feather, white, arrow, Upon death, you respawn in the previous room as Blue Baby with three Soul hearts, This is a one time use item and all new heart containers will be soul hearts, Can be used to unlock some of Blue Baby's secrets before having the character available, * item room, treasure room, item room pool, black, grey, gray, extra life, egypt, grey, gray, Upon taking damage, you have a 20% chance to gain an invulnerability shield for 7 seconds, The chance to gain a shield is affected by your luck stat and at +27 Luck it will activate every time, UNLOCK: Unlock this item by beating the Chest with Maggy, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, The recharge time of this item depends on the Rune/Soul Stone held: 2 rooms: Rune of Ansuz, Rune of Berkano, Rune of Hagalaz, Soul of Cain, 3 rooms: Rune of Algiz, Blank Rune, Soul of Magdalene, Soul of Judas, Soul of ?? After the sword falls, extra items will no longer spawn, UNLOCK: Unlock this item by defeating The Lamb as Jacob & Esau, Upon use, spawns a giant puddle of lemonade that deals 8 damage per tick to any enemies which come in contact with it, Your tears are replaced with a sword which can be swung to deal damage (Damage * 3 + Base Damage). The Binding Of Isaac's Repentance DLC has added a vast number of new items. While in this form you can walk over enemies to mark them for death. *, bag, grey, cry, blue, tear, shia paper bag sackhead, sad, Gives Isaac a cone of light infront of him that slows any enemies inside it and their tears, The light faces the direction that you are facing, not the direction you are firing, Removes Curse of Darkness for the current floor, if picked up on a floor where the curse is active, * Shop, Greed Mode Item Room, white, blue, inhaler, A purple familiar fly that follows your exact movement on a 1 second delay and deals 2 contact damage to enemies, When used, places an explosive TNT barrel next to you, The TNT barrel can be pushed and used to explode rocks or damage enemies, If used a second time in the same room while the last TNT barrel is still there, it will remotely explode the first TNT and not spawn another, REPENTANCE - Added to the Gold Chest Pool. With the release of Repentance on consoles, comes an influx of people looking for new unlocks. White poop Dips have a small Hallowed Ground aura effect, increasing your damage and fire rate while standing in it. D6, D20 etc. 8 coins = Slot Machine, While playing as Tainted Cain you get a visual interface to see what items are in the bag, allowing you to see what item will be created and swap out specific consumables, Has other uses - Will deal 3 damage to enemies it hits, and can be used to quickly push bombs and objects across rooms, Tainted Cain starts with this item, but can be used by any character after unlocking it and finding it in the item room, Cannot be used to craft another Bag of Crafting, UNLOCK: Unlock this item by defeating Delirium as Tainted Cain, While holding flip, a ghost item will appear behind item pedestals upon entering Item Rooms and Shop that cannot be interacted with, When activated, all real items in the room will be swapped with the ghost items behind them, The ghost item stays there even if you take the regular item, allowing you to use Flip to get both of them, Does nothing with item pedestals that don't have a ghost item behind them, When playing as Tainted Lazarus, activating Flip also changes you between Lazarus and Dead Lazarus, Tainted Lazarus starts with this item, but can be used by any character after unlocking it and finding it in the item room, UNLOCK: Unlock this item by defeating Delirium as Tainted Lazarus, When used, gives you an orbital flame which represents another random passive item in the game. knife, red, silver, Gives a 33% chance of converting red heart drops into soul hearts. Here is the requirements for getting 1001% completion rate in Binding of Isaac. The next room you enter he will automatically fire a massive red brimstone laser for 4 seconds, dealing huge damage, The rage resets back to zero, and the cycle continues every 5 rooms cleared, UNLOCK: Unlock this item by defeating The Beast as Tainted Azazel, When using a card, pill, or rune, you also use a copy of the last 3 cards/pills/runes you used after picking up Echo Chamber, UNLOCK: Unlock this item by defeating The Beast as Tainted Apollyon, Spawns an Old chest at the start of all future floors, Old Chests work the same as Golden Chests, requiring a key to open but contain different items, The Old chest can contain: 3 trinkets (42% chance), 1-3 soul hearts (43% chance), a random item from the Old Chest pool (10% chance) or an angel room item (5% chance), Spawns a second chest in the mirrored floor of Downpour II or Dross II, but only if you had this item before entering the floor, UNLOCK: Unlock this item by defeating The Beast as Tainted Forgotten, Each time you take damage, a red flame orbital will appear around Isaac for the remainder of the floor, up to a maximum of 6, The flames deal contact damage which scales with your tear damage, Upon reaching 6 flames, they will also start to fire tears along with Isaac, dealing a flat 3.2 damage per tear, When entering a new floor, all the flames disappear, UNLOCK: Unlock this item by defeating The Beast as Tainted Bethany, Using this item swaps you between the character you started as, and Esau, which has 3 black hearts, +2 base damage and the ability to fly, This character keeps its own separate health and items. 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